Low Dose Administration of Glutamate Triggers a Non-Apoptotic, Autophagic Response in PC12 Cells

Low Dose Administration of Glutamate Triggers a Non-Apoptotic, Autophagic Response in PC12 Cells

Background/Aims: Increasing amounts of the neurotransmitter glutamate are associated with excitotoxicity, a phenomenon related both to homeostatic processes and neurodegenerative diseases such as multiple sclerosis. Methods: PC12 cells (rat pheochromocytoma) were treated with various concentrations...

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Main Authors: Eleni Stamoula, Theofanis Vavilis, Eleni Aggelidou, Aikaterini Kaidoglou, Angeliki Cheva, Kyriakos Mellidis, Antigone Lazou, Costas Haitoglou, Maria Albani, Aristeidis Kritis
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
autophagy
Glutamate
Chaperones
Stress
Excitotoxicity
Online Access:http://www.karger.com/Article/FullText/430250

Internet

http://www.karger.com/Article/FullText/430250

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