Metallic nickel nano- and fine particles induce JB6 cell apoptosis through a caspase-8/AIF mediated cytochrome <it>c</it>-independent pathway

<p>Abstract</p> <p>Background</p> <p>Carcinogenicity of nickel compounds has been well documented. However, the carcinogenic effect of metallic nickel is still unclear. The present study investigates metallic nickel nano- and fine particle-induced apoptosis and the sign...

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Bibliographic Details
Main Authors: Castranova Vincent, Jiang Binghua, Shi Xianglin, Zhang Xingdong, Bowman Linda, Zhao Jinshun, Ding Min
Format: Article
Language:English
Published: BMC 2009-04-01
Series:Journal of Nanobiotechnology
Online Access:http://www.jnanobiotechnology.com/content/7/1/2