Mesenchymal Stem Cell Protects Injured Renal Tubular Epithelial Cells by Regulating mTOR-Mediated Th17/Treg Axis

Mesenchymal Stem Cell Protects Injured Renal Tubular Epithelial Cells by Regulating mTOR-Mediated Th17/Treg Axis

The increase in T helper 17 cell (Th17)-mediated pro-inflammatory response and decrease in regulatory T cell (Treg)-mediated anti-inflammatory effect aggravate renal tubular epithelial cell (RTEC) injury. However, increasing evidence indicated that mesenchymal stem cell (MSC) possessed the ability t...

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Bibliographic Details
Main Authors: Yongsheng Luo, Jingjing Guo, Pingbao Zhang, Yin Celeste Cheuk, Yamei Jiang, Jiyan Wang, Shihao Xu, Ruiming Rong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
mesenchymal stem cell
kidney injury
regulatory T cell
T helper 17 cell
mTOR
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.684197/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.684197/full

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