Identification of the key differential transcriptional responses of human whole blood following TLR2 or TLR4 ligation in-vitro.

Identification of the key differential transcriptional responses of human whole blood following TLR2 or TLR4 ligation in-vitro.

The use of human whole blood for transcriptomic analysis has potential advantages over the use of isolated immune cells for studying the transcriptional response to pathogens and their products. Whole blood stimulation can be carried out in a laboratory without the expertise or equipment to isolate...

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Bibliographic Details
Main Authors: Simon Blankley, Christine M Graham, Ashleigh Howes, Chloe I Bloom, Matthew P R Berry, Damien Chaussabel, Virginia Pascual, Jacques Banchereau, Marc Lipman, Anne O'Garra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4026482?pdf=render

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http://europepmc.org/articles/PMC4026482?pdf=render

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