Altered expression of polycomb group genes in glioblastoma multiforme.

The Polycomb group (PcG) proteins play a critical role in histone mediated epigenetics which has been implicated in the malignant evolution of glioblastoma multiforme (GBM). By systematically interrogating The Cancer Genome Atlas (TCGA), we discovered widespread aberrant expression of the PcG member...

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Bibliographic Details
Main Authors: Gang Li, Charles Warden, Zhaoxia Zou, Josh Neman, Joseph S Krueger, Alisha Jain, Rahul Jandial, Mike Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3829908?pdf=render