Corticotropin-Releasing Hormone Receptor Alters the Tumor Development and Growth in <i>Apcmin/+</i> Mice and in a Chemically-Induced Model of Colon Cancer

Corticotropin-Releasing Hormone Receptor Alters the Tumor Development and Growth in <i>Apcmin/+</i> Mice and in a Chemically-Induced Model of Colon Cancer

The neuroendocrine circuit of the corticotropin-releasing hormone (CRH) family peptides, via their cognate receptors CRHR1 and CRHR2, copes with psychological stress. However, peripheral effects of the CRH system in colon cancer remains elusive. Thus, we investigate the role of CRHR1 and CRHR2 in co...

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Bibliographic Details
Main Authors: Yunna Lee, Elise L. Ma, Marisa Patel, Gayoung Kim, Cody Howe, Charalabos Pothoulakis, Yong Sung Kim, Eunok Im, Sang Hoon Rhee
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
cyclooxygenase 2
neuropeptide
stress
tumorigenicity
gastrointestinal
colitis
Online Access:https://www.mdpi.com/1422-0067/22/3/1043

Internet

https://www.mdpi.com/1422-0067/22/3/1043

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