Temporal evolution of heme oxygenase-1 expression in reactive astrocytes and microglia in response to traumatic brain injury

Temporal evolution of heme oxygenase-1 expression in reactive astrocytes and microglia in response to traumatic brain injury

Heme oxygenase-1 (HO-1) is an inducible enzyme that catabolizes heme into biliverdin (which is converted to bilirubin), carbon monoxide, and free iron. HO-1 and its downstream molecules have antioxidant and anti-inflammatory functions, making the effects of HO-1 difficult to predict. It is unknown i...

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Bibliographic Details
Main Authors: Alexander Morita, Amandine Jullienne, Arjang Salehi, Mary Hamer, Emon Javadi, Yasir Alsarraj, Jiping Tang, John H. Zhang, William J. Pearce, André Obenaus
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2020-03-01
Series:Brain Hemorrhages
Subjects:
Astrocytes
Heme oxygenase-1
Microglia
Traumatic brain injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2589238X20300085

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http://www.sciencedirect.com/science/article/pii/S2589238X20300085

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