Cardiolipin Synthesis and Outer Membrane Localization Are Required for Shigella flexneri Virulence
Cardiolipin, an anionic phospholipid that resides at the poles of the inner and outer membranes, is synthesized primarily by the putative cardiolipin synthase ClsA in Shigella flexneri. An S. flexneri clsA mutant had no cardiolipin detected within its membrane, grew normally in vitro, and invaded cu...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2017-08-01
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| Series: | mBio |
| Online Access: | http://mbio.asm.org/cgi/content/full/8/4/e01199-17 |