Extracellular and intracellular mechanisms of mechanotransduction in three-dimensionally embedded rat chondrocytes.

Extracellular and intracellular mechanisms of mechanotransduction in three-dimensionally embedded rat chondrocytes.

Articular cartilage homeostasis involves modulation of chondrocyte matrix synthesis in response to mechanical stress (MS). We studied extracellular and intracellular mechanotransduction pathways mediating this response.We first confirmed rapid up-regulation of the putative chondro-protective cytokin...

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Bibliographic Details
Main Authors: Suguru Shioji, Shinji Imai, Kosei Ando, Kousuke Kumagai, Yoshitaka Matsusue
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4257595?pdf=render

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http://europepmc.org/articles/PMC4257595?pdf=render

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