Ni(II)-catalyzed asymmetric alkenylations of ketimines

Chiral allylic amines are often encountered in bioactive compounds and can be conveniently transformed into other chiral amines. Here, the authors report nickel-catalyzed enantioselective addition and addition/ring-expansion of alkenylboronic acids to ketimines providing a range of valuable chiral a...

Full description

Bibliographic Details
Main Authors: Mao Quan, Xiaoxiao Wang, Liang Wu, Ilya D. Gridnev, Guoqiang Yang, Wanbin Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2018-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-04645-3