Hydroxycarboxylic Acid Receptor 2 Is a Zika Virus Restriction Factor That Can Be Induced by Zika Virus Infection Through the IRE1-XBP1 Pathway

Hydroxycarboxylic Acid Receptor 2 Is a Zika Virus Restriction Factor That Can Be Induced by Zika Virus Infection Through the IRE1-XBP1 Pathway

Zika virus (ZIKV) is an emerging arthropod-borne virus and belongs to the Flaviviridae family. The infection of ZIKV has become the global health crisis because of its rapid spread and association with severe neurological disorders, including congenital microcephaly and Guillain-Barre Syndrome. To i...

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Bibliographic Details
Main Authors: Xiaocao Ma, Xin Luo, Shili Zhou, Yanxia Huang, Cancan Chen, Changbai Huang, Li Shen, Ping Zhang, Chao Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
ZIKV
HCAR2
IRE1-XBP1
CRISPR/Cas9
restriction factor
viral replication
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00480/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00480/full

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