Assembly of an Evolutionarily Conserved Alternative Proteasome Isoform in Human Cells
Targeted intracellular protein degradation in eukaryotes is largely mediated by the proteasome. Here, we report the formation of an alternative proteasome isoform in human cells, previously found only in budding yeast, that bears an altered subunit arrangement in the outer ring of the proteasome cor...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-03-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124716302030 |