Role of duplicate genes in robustness against deleterious human mutations.
It is now widely recognized that robustness is an inherent property of biological systems [1],[2],[3]. The contribution of close sequence homologs to genetic robustness against null mutations has been previously demonstrated in simple organisms [4],[5]. In this paper we investigate in detail the con...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-03-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2265532?pdf=render |