NADPH Oxidase Biology and the Regulation of Tyrosine Kinase Receptor Signaling and Cancer Drug Cytotoxicity

The outdated idea that reactive oxygen species (ROS) are only dangerous products of cellular metabolism, causing toxic and mutagenic effects on cellular components, is being replaced by the view that ROS have several important functions in cell signaling. In aerobic organisms, ROS can be generated f...

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Bibliographic Details
Main Authors: Rafael Paletta-Silva, Nathália Rocco-Machado, José Roberto Meyer-Fernandes
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/14/2/3683