Comparable Long-Term Rabies Immunity in Foxes after IntraMuscular and Oral Application Using a Third-Generation Oral Rabies Virus Vaccine

Comparable Long-Term Rabies Immunity in Foxes after IntraMuscular and Oral Application Using a Third-Generation Oral Rabies Virus Vaccine

The live genetically-engineered oral rabies virus (RABV) variant SPBN GASGAS induces long-lasting immunity in foxes and protection against challenge with an otherwise lethal dose of RABV field strains both after experimental oral and parenteral routes of administration. Induction of RABV-specific bi...

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Bibliographic Details
Main Authors: Verena te Kamp, Virginia Friedrichs, Conrad M. Freuling, Ad Vos, Madlin Potratz, Antonia Klein, Luca M. Zaeck, Elisa Eggerbauer, Peter Schuster, Christian Kaiser, Steffen Ortmann, Antje Kretzschmar, Katharina Bobe, Michael R. Knittler, Anca Dorhoi, Stefan Finke, Thomas Müller
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Vaccines
Subjects:
foxes
oral vaccination
SPBN GASGAS
neutralizing and binding antibodies
immunoglobulin isotypes
interferon gamma
Online Access:https://www.mdpi.com/2076-393X/9/1/49

Internet

https://www.mdpi.com/2076-393X/9/1/49

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