Mechanisms of oxidative stress and alterations in gene expression by Libby six-mix in human mesothelial cells

<p>Abstract</p> <p>Background</p> <p>Exposures to an amphibole fiber in Libby, Montana cause increases in malignant mesothelioma (MM), a tumor of the pleural and peritoneal cavities with a poor prognosis. Affymetrix microarray/GeneSifter analysis was used to determine a...

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Bibliographic Details
Main Authors: Hillegass Jedd M, Shukla Arti, MacPherson Maximilian B, Lathrop Sherrill A, Alexeeva Vlada, Perkins Timothy N, van der Vliet Albert, Vacek Pamela M, Gunter Mickey E, Mossman Brooke T
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Particle and Fibre Toxicology
Online Access:http://www.particleandfibretoxicology.com/content/7/1/26