Alcohol Consumption and Risk of Common Autoimmune Inflammatory Diseases—Evidence From a Large-Scale Genetic Analysis Totaling 1 Million Individuals

Alcohol Consumption and Risk of Common Autoimmune Inflammatory Diseases—Evidence From a Large-Scale Genetic Analysis Totaling 1 Million Individuals

Purpose: Observational studies have suggested a protective effect of alcohol intake with autoimmune disorders, which was not supported by Mendelian randomization (MR) analyses that used only a few (<20) instrumental variables.Methods: We systemically interrogated a putative causal relationshi...

Full description

Bibliographic Details
Main Authors: Xia Jiang, Zhaozhong Zhu, Ali Manouchehrinia, Tomas Olsson, Lars Alfredsson, Ingrid Kockum
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Genetics
Subjects:
Mendelian Randomization (MR)
alcohol consumption amount
excessive drinking
autoimmune disease
genetic correlation
large-scale genetic analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.687745/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.687745/full

Similar Items