Control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation

Purely elastic biomimetic soft materials are used to characterize the mechanical response of cells, but do not resemble real tissues. Here the authors develop a viscoelastic solid hydrogel, based on polyacrylamide, that can be tuned to closely resemble soft tissue, and show the influence of viscous...

Full description

Bibliographic Details
Main Authors: Elisabeth E. Charrier, Katarzyna Pogoda, Rebecca G. Wells, Paul A. Janmey
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-02906-9