Engineering a Vascularized 3D Hybrid System to Model Tumor-Stroma Interactions in Breast Cancer

Engineering a Vascularized 3D Hybrid System to Model Tumor-Stroma Interactions in Breast Cancer

The stromal microenvironment of breast tumors, namely the vasculature, has a key role in tumor development and metastatic spread. Tumor angiogenesis is a coordinated process, requiring the cooperation of cancer cells, stromal cells, such as fibroblasts and endothelial cells, secreted factors and the...

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Bibliographic Details
Main Authors: Filipa C. Teixeira, Sara Chaves, Ana Luísa Torres, Cristina C. Barrias, Sílvia J. Bidarra
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
hydrogel
alginate
vascularized stroma
outgrowth endothelial cells
angiogenesis
tissue engineering
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.647031/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2021.647031/full

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