Cytoplasmic Localization Isoform of Cyclin Y Enhanced the Metastatic Ability of Lung Cancer via Regulating Tropomyosin 4

Cytoplasmic Localization Isoform of Cyclin Y Enhanced the Metastatic Ability of Lung Cancer via Regulating Tropomyosin 4

Cyclin Y (CCNY) is a novel cyclin and highly conserved in metazoan species. Previous studies from our and other laboratory indicate that CCNY play a crucial role in tumor progression. There are two CCNY isoform which has different subcellular distributions, with cytoplasmic isoform (CCNYc) and membr...

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Bibliographic Details
Main Authors: Xiaoting Zhao, Mei Jiang, Yu Teng, Jie Li, Zhefeng Li, Wende Hao, Hongyu Zhao, Chenghong Yin, Wentao Yue
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
lung cancer
cytoplasmic isoform cyclin Y
metastasis
PFTK1
tropomyosin 4
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.684819/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.684819/full

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