Abnormal mitosis in reactive astrocytes

Abnormal mitosis in reactive astrocytes

Abstract Although abnormal mitosis with disarranged metaphase chromosomes or many micronuclei in astrocytes (named “Alzheimer I type astrocytes” and later “Creutzfeldt-Peters cells”) have been known for nearly 100 years, the origin and mechanisms of this pathology remain elusive. In experimental bra...

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Bibliographic Details
Main Authors: Alexander Sosunov, Xiaoping Wu, Robert McGovern, Charles Mikell, Guy M. McKhann, James E. Goldman
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Acta Neuropathologica Communications
Subjects:
Astrocytes
Mitosis
Mitotic spindles
Polyploidy
Creutzfeldt-Peters cells
Online Access:http://link.springer.com/article/10.1186/s40478-020-00919-4

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http://link.springer.com/article/10.1186/s40478-020-00919-4

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