A thymidine kinase-deleted bovine herpesvirus 5 establishes latent infection but reactivates poorly in a sheep model Recombinante do herpesvírus bovino tipo 5 com deleção na timidina quinase estabelece infecção latente porém reativa ineficientemente em ovinos

A thymidine kinase-deleted bovine herpesvirus 5 establishes latent infection but reactivates poorly in a sheep model Recombinante do herpesvírus bovino tipo 5 com deleção na timidina quinase estabelece infecção latente porém reativa ineficientemente em ovinos

The ability of thymidine kinase (tk)-deleted recombinant bovine herpesvirus 5 (BoHV-5tkΔ) to establish and reactivate latent infection was investigated in lambs. During acute infection, the recombinant virus replicated moderately in the nasal mucosa, yet to lower titers than the parental st...

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Bibliographic Details
Main Authors: Gustavo C. Cadore, Marcelo Weiss, Deniz Anziliero, Mário Celso S. Brum, Rudi Weiblen, Eduardo F. Flores
Format: Article
Language:English
Published: Colégio Brasileiro de Patologia Animal (CBPA) 2013-03-01
Series:Pesquisa Veterinária Brasileira
Subjects:
BoHV-5
recombinante
TK
latência
qPCR
recombinant
latency
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2013000300010

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2013000300010

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