Safety Pharmacology Study of Medicines Used for Febrile Syndrome Management in Children

Safety Pharmacology Study of Medicines Used for Febrile Syndrome Management in Children

Summary. Safety pharmacology studies of paediatric medicines are an important stage in the life cycle of drugs.The purpose of the study was to analyse and compare the safety pharmacology profiles of the recommended paediatric dosage regimens of a fixed ibuprofen (IBU)/paracetamol (PAR) combination a...

Full description

Bibliographic Details
Main Authors: K. L. Kryshen, A. E. Moshkov, M. N. Demyanovskiy, M. A. Kovaleva
Format: Article
Language:Russian
Published: Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation  2020-09-01
Series:Безопасность и риск фармакотерапии
Subjects:
preclinical studies
juvenile rats
ibuprofen/paracetamol fi xed combination
hepatotoxicity
nephrotoxicity
cardiotoxicity
neurotoxicity
respiratory system
Online Access:https://www.risksafety.ru/jour/article/view/194

Internet

https://www.risksafety.ru/jour/article/view/194

Similar Items