Glypican-3 Targeting Immunotoxins for the Treatment of Liver Cancer

Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer, yet no effective therapeutics exist. This review provides an overview of the recent development of recombinant immunotoxins for the treatment of glypican-3 (GPC3) expressing HCC. GPC3 is a cell surface heparan sulfate pr...

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Bibliographic Details
Main Authors: Bryan D. Fleming, Mitchell Ho
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/8/10/274