Delayed internalization and lack of recycling in a beta<sub>2</sub>-adrenergic receptor fused to the G protein alpha-subunit

Delayed internalization and lack of recycling in a beta<sub>2</sub>-adrenergic receptor fused to the G protein alpha-subunit

<p>Abstract</p> <p>Background</p> <p>Chimeric proteins obtained by the fusion of a G protein-coupled receptor (GPCR) sequence to the N-terminus of the G protein α-subunit have been extensively used to investigate several aspects of GPCR signalling. Although both the rec...

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Bibliographic Details
Main Authors:	Floridi Aristide, Serafino Annalucia, Casella Ida, Batassa Enrico M, Di Certo Maria, Passananti Claudio, Molinari Paola, Mattei Elisabetta
Format:	Article
Language:	English
Published:	BMC 2008-10-01
Series:	BMC Cell Biology
Online Access:	http://www.biomedcentral.com/1471-2121/9/56

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