Delayed internalization and lack of recycling in a beta<sub>2</sub>-adrenergic receptor fused to the G protein alpha-subunit
<p>Abstract</p> <p>Background</p> <p>Chimeric proteins obtained by the fusion of a G protein-coupled receptor (GPCR) sequence to the N-terminus of the G protein α-subunit have been extensively used to investigate several aspects of GPCR signalling. Although both the rec...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-10-01
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Series: | BMC Cell Biology |
Online Access: | http://www.biomedcentral.com/1471-2121/9/56 |