Crowding Effects on the Structure and Dynamics of the Intrinsically Disordered Nuclear Chromatin Protein NUPR1

Crowding Effects on the Structure and Dynamics of the Intrinsically Disordered Nuclear Chromatin Protein NUPR1

The intracellular environment is crowded with macromolecules, including sugars, proteins and nucleic acids. In the cytoplasm, crowding effects are capable of excluding up to 40% of the volume available to any macromolecule when compared to dilute conditions. NUPR1 is an intrinsically disordered prot...

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Bibliographic Details
Main Authors: Alessio Bonucci, Martina Palomino-Schätzlein, Paula Malo de Molina, Arantxa Arbe, Roberta Pierattelli, Bruno Rizzuti, Juan L. Iovanna, José L. Neira
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
crowders
nuclear protein 1
intrinsically disordered protein
electron paramagnetic resonance
NMR
spin labelling
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.684622/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.684622/full

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