A systems biology approach to identify niche determinants of cellular phenotypes

Recent reports indicate a dominant role for cellular microenvironment or niche for stably maintaining cellular phenotypic states. Identification of key niche mediated signaling that maintains stem cells in specific phenotypic states remains a challenge, mainly due to the complex and dynamic nature o...

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Bibliographic Details
Main Authors: Srikanth Ravichandran, Satoshi Okawa, Susana Martínez Arbas, Antonio del Sol
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Stem Cell Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506116301210