Variation sites at the HLA-G 3' untranslated region confer differential susceptibility to HIV/HPV co-infection and aneuploidy in cervical cell.

Post-transcriptional regulatory elements associated with transcript degradation or transcript instability have been described at the 3' untranslated region (3'UTR) of the HLA-G gene. Considering that HPV infection and aneuploidy, which causes gene instability, are associated with cervical...

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Main Authors: Fernanda Silva Medeiros, Albert Eduardo Silva Martins, Renan Garcia Gomes, Sávio Augusto Vieira de Oliveira, Stefan Welkovic, Magda Maruza, Maria Luiza Bezerra Menezes, Ricardo Arraes de Alencar Ximenes, George Tadeu Nunes Diniz, Eduardo Antônio Donadi, Norma Lucena-Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6168131?pdf=render