ATF5, a putative therapeutic target for the mitochondrial DNA 3243A > G mutation-related disease

ATF5, a putative therapeutic target for the mitochondrial DNA 3243A > G mutation-related disease

Abstract The mitochondrial DNA m.3243A > G mutation is well-known to cause a variety of clinical phenotypes, including diabetes, deafness, and osteoporosis. Here, we report isolation and expansion of urine-derived stem cells (USCs) from patients carrying the m.3243A > G mutation, which demonst...

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Bibliographic Details
Main Authors: Xinpei Gao, Zhixin Jiang, Xinfeng Yan, Jiping Liu, Fengwen Li, Peng Liu, Jialu Li, Yuehua Wei, Yi Eve Sun, Yinan Zhang, Congrong Wang
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03993-1

Internet

https://doi.org/10.1038/s41419-021-03993-1

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