Enhance the Immune Checkpoint Inhibitors Efficacy with Radiotherapy Induced Immunogenic Cell Death: A Comprehensive Review and Latest Developments

Enhance the Immune Checkpoint Inhibitors Efficacy with Radiotherapy Induced Immunogenic Cell Death: A Comprehensive Review and Latest Developments

The immunogenic cell death (ICD) is defined as a regulated cell death able to induce an adaptive immunity. It depends on different parameters including sufficient antigenicity, adjuvanticity and favorable microenvironment conditions. Radiation therapy (RT), a pillar of modern cancer treatment, is be...

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Bibliographic Details
Main Authors: Adrien Procureur, Audrey Simonaggio, Jean-Emmanuel Bibault, Stéphane Oudard, Yann-Alexandre Vano
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
radiotherapy
radioimmunotherapy
immunogenic cell death
immune checkpoint inhibitors
combination therapy
cancer treatment
Online Access:https://www.mdpi.com/2072-6694/13/4/678

Internet

https://www.mdpi.com/2072-6694/13/4/678

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