Expression of hypoxia inducible factor-1α (HIF-1α) gene and apoptosis in the heart induced by systemic hypoxia

Aim This study explored the expression of HIF-1α in hypoxic cardiac muscle in mice, and observed the evidence of apoptosis in hypoxia induced cardiomyocyte. Methods Male Sprague-Dawley rats, were randomized into 7 groups (n = 4 per group): control normoxia group that was exposed to atmospheric oxy...

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Bibliographic Details
Main Authors: Siufui Hendrawan, Sri W.A. Jusman, Frans Ferdinal, Ani R. Prijanti, Septelia I. Wanandi, Mohamad Sadikin
Format: Article
Language:English
Published: Faculty of Medicine Universitas Indonesia 2009-05-01
Series:Medical Journal of Indonesia
Online Access:http://mji.ui.ac.id/journal/index.php/mji/article/view/344