Optogenetic Evocation of Field Inhibitory Postsynaptic Potentials in Hippocampal Slices: A Simple and Reliable Approach for Studying Pharmacological Effects on GABAA and GABAB Receptor-Mediated Neurotransmission

The GABAergic system is the main source of inhibition in the mammalian brain. Consequently, much effort is still made to develop new modulators of GABAergic synaptic transmission. In contrast to glutamatergic postsynaptic potentials (PSPs), accurate monitoring of GABA receptor-mediated PSPs (GABAR-P...

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Bibliographic Details
Main Authors: Julien eDine, Claudia eKühne, Jan M Deussing, Matthias eEder
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
CA1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00002/full