A graph-based algorithm for estimating clonal haplotypes of tumor sample from sequencing data

A graph-based algorithm for estimating clonal haplotypes of tumor sample from sequencing data

Abstract Background Haplotype phasing is an important step in many bioinformatics workflows. In cancer genomics, it is suggested that reconstructing the clonal haplotypes of a tumor sample could facilitate a comprehensive understanding of its clonal architecture and further provide valuable referenc...

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Bibliographic Details
Main Authors: Yixuan Wang, Xuanping Zhang, Shuai Ding, Yu Geng, Jianye Liu, Zhongmeng Zhao, Rong Zhang, Xiao Xiao, Jiayin Wang
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Medical Genomics
Subjects:
Cancer genomics
Haplotype phasing
Clonal haplotype
Computational pipeline
Sequencing data analysis
Online Access:http://link.springer.com/article/10.1186/s12920-018-0457-4

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http://link.springer.com/article/10.1186/s12920-018-0457-4

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