AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication

AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication

Summary: Autism susceptibility candidate 2 (AUTS2), a risk gene for autism spectrum disorders (ASDs), is implicated in telencephalon development. Because AUTS2 is also expressed in the cerebellum where defects have been linked to ASDs, we investigated AUTS2 functions in the cerebellum. AUTS2 is spec...

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Bibliographic Details
Main Authors: Kunihiko Yamashiro, Kei Hori, Esther S.K. Lai, Ryo Aoki, Kazumi Shimaoka, Nariko Arimura, Saki F. Egusa, Asami Sakamoto, Manabu Abe, Kenji Sakimura, Takaki Watanabe, Naofumi Uesaka, Masanobu Kano, Mikio Hoshino
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:iScience
Subjects:
Molecular Neuroscience
Developmental Neuroscience
Cellular Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220310178

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http://www.sciencedirect.com/science/article/pii/S2589004220310178

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