Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis

Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis

It is currently unknown whether the molecular steps of large dense-core vesicle (LDCV) docking and priming are identical to the corresponding reactions in synaptic vesicle (SV) exocytosis. Munc13s are essential for SV docking and priming, and we systematically analyzed their role in LDCV exocytosis...

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Bibliographic Details
Main Authors: Kwun Nok M Man, Cordelia Imig, Alexander M Walter, Paulo S Pinheiro, David R Stevens, Jens Rettig, Jakob B Sørensen, Benjamin H Cooper, Nils Brose, Sonja M Wojcik
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-11-01
Series:eLife
Subjects:
munc13
baiap3
large dense-core vesicle
neuroendocrine
priming
docking
Online Access:https://elifesciences.org/articles/10635

Internet

https://elifesciences.org/articles/10635

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