Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus

Decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Here the authors provide evidence that environmental enrichment delays age-related DNA methylation alterations in the mouse hippocampus.

Bibliographic Details
Main Authors: Sara Zocher, Rupert W. Overall, Mathias Lesche, Andreas Dahl, Gerd Kempermann
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23993-1