Metabolic engineering of Ashbya gossypii for deciphering the de novo biosynthesis of γ-lactones

Metabolic engineering of Ashbya gossypii for deciphering the de novo biosynthesis of γ-lactones

Abstract Background Lactones are highly valuable cyclic esters of hydroxy fatty acids that find application as pure fragrances or as building blocks of speciality chemicals. While chemical synthesis often leads to undesired racemic mixtures, microbial production allows obtaining optically pure lacto...

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Bibliographic Details
Main Authors: Rui Silva, Tatiana Q. Aguiar, Eduardo Coelho, Alberto Jiménez, José Luis Revuelta, Lucília Domingues
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Microbial Cell Factories
Subjects:
Volatile organic compounds
γ-Lactones
Ashbya gossypii
De novo biosynthesis
Metabolic engineering
Fatty acid biosynthesis
Online Access:http://link.springer.com/article/10.1186/s12934-019-1113-1

Internet

http://link.springer.com/article/10.1186/s12934-019-1113-1

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