Variable expressivity of the tumour suppressor protein TRP53 in cryopreserved human blastocysts

<p>Abstract</p> <p>In a mouse model, in vitro fertilization or extended embryo culture leads to the increased expression of TRP53 in susceptible embryos. Ablation of the TRP53 gene improved embryo viability indicating that increased expression of TRP53 is a cause of the reduction o...

Full description

Bibliographic Details
Main Authors: Stojanov Tomas, Chami Omar, Chandrakanthan Vashe, O'Neill Chris
Format: Article
Language:English
Published: BMC 2007-10-01
Series:Reproductive Biology and Endocrinology
Online Access:http://www.rbej.com/content/5/1/39