Cellular senescence in musculoskeletal homeostasis, diseases, and regeneration

Abstract Emerging insights into cellular senescence highlight the relevance of senescence in musculoskeletal disorders, which represent the leading global cause of disability. Cellular senescence was initially described by Hayflick et al. in 1961 as an irreversible nondividing state in in vitro cell...

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Bibliographic Details
Main Authors: Mei Wan, Elise F. Gray-Gaillard, Jennifer H. Elisseeff
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-021-00164-y