Pre-clinical antigenicity studies of an innovative multivalent vaccine for human visceral leishmaniasis.

The notion that previous infection by Leishmania spp. in endemic areas leads to robust anti-Leishmania immunity, supports vaccination as a potentially effective approach to prevent disease development. Nevertheless, to date there is no vaccine available for human leishmaniasis. We optimized and asse...

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Main Authors: Pedro Cecílio, Begoña Pérez-Cabezas, Laura Fernández, Javier Moreno, Eugenia Carrillo, José M Requena, Epifanio Fichera, Steven G Reed, Rhea N Coler, Shaden Kamhawi, Fabiano Oliveira, Jesus G Valenzuela, Luigi Gradoni, Reinhard Glueck, Gaurav Gupta, Anabela Cordeiro-da-Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5720812?pdf=render