Distributions of transposable elements reveal hazardous zones in mammalian introns.

Comprising nearly half of the human and mouse genomes, transposable elements (TEs) are found within most genes. Although the vast majority of TEs in introns are fixed in the species and presumably exert no significant effects on the enclosing gene, some markedly perturb transcription and result in d...

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Bibliographic Details
Main Authors: Ying Zhang, Mark T Romanish, Dixie L Mager
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3088655?pdf=render