Tigecycline resistance may be associated with dysregulated response to stress in Mycobacterium abscessus

Previously, we characterized 7C, a laboratory-derived tigecycline-resistant mutant of Mycobacterium abscessus ATCC 19977, and found that the resistance was conferred by a mutation in MAB_3542c, which encodes an RshA-like protein. In M. tuberculosis, RshA is an anti-sigma factor that negatively regul...

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Bibliographic Details
Main Authors: Hien Fuh Ng, Yun Fong Ngeow, Sook Fan Yap, Thaw Zin, Joon Liang Tan
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:International Journal of Medical Microbiology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1438422119301547