Tigecycline resistance may be associated with dysregulated response to stress in Mycobacterium abscessus
Previously, we characterized 7C, a laboratory-derived tigecycline-resistant mutant of Mycobacterium abscessus ATCC 19977, and found that the resistance was conferred by a mutation in MAB_3542c, which encodes an RshA-like protein. In M. tuberculosis, RshA is an anti-sigma factor that negatively regul...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
|
Series: | International Journal of Medical Microbiology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1438422119301547 |