A New Approach for Loading Anticancer Drugs Into Mesenchymal Stem Cell-Derived Exosome Mimetics for Cancer Therapy

A New Approach for Loading Anticancer Drugs Into Mesenchymal Stem Cell-Derived Exosome Mimetics for Cancer Therapy

Exosomes derived from mesenchymal stem cells (MSCs) have been evaluated for their potential to be used as drug delivery vehicles. Synthetically personalized exosome mimetics (EMs) could be the alternative vesicles for drug delivery. In this study, we aimed to isolate EMs from human MSCs. Cells were...

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Bibliographic Details
Main Authors: Senthilkumar Kalimuthu, Prakash Gangadaran, Ramya Lakshmi Rajendran, Liya Zhu, Ji Min Oh, Ho Won Lee, Arunnehru Gopal, Se Hwan Baek, Shin Young Jeong, Sang-Woo Lee, Jaetae Lee, Byeong-Cheol Ahn
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Pharmacology
Subjects:
MSC
exosome mimetic
paclitaxel
breast cancer
MDA-MB-231
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01116/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01116/full

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