Bioinformatics analysis of bacterial annexins--putative ancestral relatives of eukaryotic annexins.

Annexins are Ca(2+)-binding, membrane-interacting proteins, widespread among eukaryotes, consisting usually of four structurally similar repeated domains. It is accepted that vertebrate annexins derive from a double genome duplication event. It has been postulated that a single domain annexin, if fo...

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Bibliographic Details
Main Authors: Praveen Kumar Kodavali, Małgorzata Dudkiewicz, Sławomir Pikuła, Krzysztof Pawłowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3894181?pdf=render