Circadian transcription contributes to core period determination in Drosophila.

The Clock-Cycle (CLK-CYC) heterodimer constitutes a key circadian transcription complex in Drosophila. CYC has a DNA-binding domain but lacks an activation domain. Previous experiments also indicate that most of the transcriptional activity of CLK-CYC derives from the glutamine-rich region of its pa...

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Bibliographic Details
Main Authors: Sebastian Kadener, Jerome S Menet, Rebecca Schoer, Michael Rosbash
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-05-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2386838?pdf=render