Characterization of the tandem CWCH2 sequence motif: a hallmark of inter-zinc finger interactions

<p>Abstract</p> <p>Background</p> <p>The C2H2 zinc finger (ZF) domain is widely conserved among eukaryotic proteins. In Zic/Gli/Zap1 C2H2 ZF proteins, the two N-terminal ZFs form a single structural unit by sharing a hydrophobic core. This structural unit defines a new...

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Bibliographic Details
Main Authors: Aruga Jun, Hatayama Minoru
Format: Article
Language:English
Published: BMC 2010-02-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/10/53