Comprehensive analysis of aberrantly expressed profiles of mRNA and its relationship with serum galactose-deficient IgA1 level in IgA nephropathy

Comprehensive analysis of aberrantly expressed profiles of mRNA and its relationship with serum galactose-deficient IgA1 level in IgA nephropathy

Abstract Background Immunoglobulin A nephropathy (IgAN) is the leading cause of end-stage kidney disease. Previous mRNA microarray profiling studies of IgAN revealed inconsistent data. We sought to identify the aberrantly expressed genes and biological pathways by integrating IgAN gene expression da...

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Bibliographic Details
Main Authors: Youxia Liu, Xiangchun Liu, Junya Jia, Jie Zheng, Tiekun Yan
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Journal of Translational Medicine
Subjects:
IgA nephropathy
mRNA microarray
Differential gene expression
RNA-deep sequencing
Galactose-deficient IgA1
Online Access:http://link.springer.com/article/10.1186/s12967-019-2064-3

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http://link.springer.com/article/10.1186/s12967-019-2064-3

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