4-Amino-2-trifluoromethyl-phenyl retinate induced differentiation of human myelodysplastic syndromes SKM-1 cell lines by up-regulating DDX23

4-Amino-2-trifluoromethyl-phenyl retinate induced differentiation of human myelodysplastic syndromes SKM-1 cell lines by up-regulating DDX23

Myelodysplastic syndrome (MDS) is a heterogeneously cloned hematopoietic stem cell malignancy with a high risk of developing acute myeloid leukemia (AML). 4-amino-2-trifluoromethyl-phenyl resinate (ATPR), a novel all-trans retinoic acid (ATRA) derivative designed in our group, was proved to be a tum...

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Bibliographic Details
Main Authors: Cong Wang, Ke Wang, Shu-Fang Li, Su-Jing Song, Yan Du, Ruo-Wen Niu, Xue-Wen Qian, Xiao-Qing Peng, Fei-Hu Chen
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
4-Amino-2-trifluoromethyl-phenyl retinate (ATPR)
Differentiation
MDS
SKM-1 cells
DDX23
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219353582

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http://www.sciencedirect.com/science/article/pii/S0753332219353582

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