Synthesis and in Vitro Antiproliferative Activity of New Phenylaminoisoquinolinequinones against Cancer Cell Lines

A variety of phenylaminoisoquinolinequinones were synthesized and tested for their antiproliferative activity against three human-tumor derived cancer cell lines. The new aminoquinones were prepared from 4-methoxycarbonyl-3-methylisoquinoline-5,8-quinone (1) via acid-induced amination and brominatio...

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Bibliographic Details
Main Authors: Virginia Delgado, Andrea Ibacache, Verónica Arancibia, Cristina Theoduloz, Jaime A. Valderrama
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/1/721